| 01 | California Department of Health Care Servicesof $85.1B total | $85.1B | $92.8B | −8% | same |
| 02 | Lockheed Martin Corporationof $69.1B total | $69.1B | $561.9M | — | ▲ 255 |
| 03 | NYS Department of Healthof $55.2B total | $55.2B | $59B | −6% | ▼ 1 |
| 04 | Health & Human SVC Commn TXof $50.4B total | $50.4B | $52.9B | −5% | ▼ 1 |
| 05 | PA Department of Human Servicesof $37.5B total | $37.5B | $37.1B | +1% | same |
| 06 | Central States Pension Planof $35.8B total | $35.8B | — | — | — |
| 07 | RTX Corporationof $26.8B total | $26.8B | $10.5M | — | ▲ 832 |
| 08 | Department of Social Services Californiaof $26.5B total | $26.5B | $27.1B | −2% | ▼ 2 |
| 09 | General Dynamics Corporationof $25.9B total | $25.9B | — | — | — |
| 10 | Ohio Department of Medicaidof $24.6B total | $24.6B | $25B | −2% | ▼ 3 |
| 11 | Michigan Department of Health and Human Servicesof $23.9B total | $23.9B | $24.2B | −1% | ▼ 2 |
| 12 | Florida Agency for Health Care Administrationof $22.7B total | $22.7B | $24.9B | −9% | ▼ 4 |
| 13 | North Carolina Department of Health & Human Servicesof $22.7B total | $22.7B | $21.8B | +4% | ▼ 3 |
| 14 | The Boeing Companyof $22.6B total | $22.6B | $508.4K | — | ▲ 868 |
| 15 | Illinois Department of Healthcare & Family Servicesof $20.9B total | $20.9B | $18B | +16% | ▼ 2 |
| 16 | Department of Social & Health Servicesof $20.3B total | $20.3B | $17.4B | +16% | ▼ 1 |
| 17 | The Commonwealth of Massachusettsof $19.6B total | $19.6B | $18.9B | +4% | ▼ 5 |
| 18 | New Jersey Department of Human Servicesof $19.3B total | $19.3B | $20B | −4% | ▼ 7 |
| 19 | Arizona Health Care Cost Containment Systemof $19.1B total | $19.1B | $18B | +6% | ▼ 5 |
| 20 | UnitedHealth Groupof $17B total | $17B | $37.4B | −55% | ▼ 16 |
| 21 | Health Services Kentucky Cabinet forof $16.7B total | $16.7B | $14.8B | +13% | ▼ 4 |
| 22 | Indiana Family and Social Servof $15.9B total | $15.9B | $15.7B | +1% | ▼ 6 |
| 23 | International Bank for Reconstruction and Developmentof $15.8B total | $15.8B | $9.1B | +73% | ▲ 7 |
| 24 | Department of Social Services Missoof $15.6B total | $15.6B | $13.1B | +19% | ▼ 2 |
| 25 | Northrop Grumman Systems Corpof $15.2B total | $15.2B | $223.9M | — | ▲ 491 |
| 26 | VA Department of Medical Assistance Serviceof $14.6B total | $14.6B | $12.4B | +18% | ▼ 3 |
| 27 | New York State Office of Temporary & Disability Assistanceof $14.4B total | $14.4B | $14.2B | +1% | ▼ 8 |
| 28 | Minnesota Department of Human Servicesof $14.3B total | $14.3B | $13.8B | +3% | ▼ 8 |
| 29 | Lousiana Department of Healthof $14.1B total | $14.1B | $11.4B | +23% | ▼ 3 |
| 30 | Maryland Department of Healthof $12.4B total | $12.4B | — | — | — |
| 31 | Georgia Department of Community Healthof $12.3B total | $12.3B | $11.7B | +4% | ▼ 7 |
| 32 | Oregon Health Authority-Public Healthof $11.9B total | $11.9B | $10.8B | +10% | ▼ 5 |
| 33 | Huntington Ingalls Industries, Inc.of $11.1B total | $11.1B | $53.5K | — | ▲ 874 |
| 34 | State of Wisconsin Department of Health Servicesof $10.9B total | $10.9B | $11.6B | −6% | ▼ 9 |
| 35 | Mckesson Corporationof $10.1B total | $10.1B | — | — | — |
| 36 | Florida Department of Children and Familiesof $10.1B total | $10.1B | $7.7B | +30% | same |
| 37 | Mckesson Corporationof $9.5B total | $9.5B | $8.4B | +14% | ▼ 4 |
| 38 | Finance & Administration Tennessee Deparof $9.4B total | $9.4B | $9.4B | 0% | ▼ 10 |
| 39 | Department of Social Services Connecticutof $9B total | $9B | $8.4B | +8% | ▼ 5 |
| 40 | State of Colorado - Dept of Health Care Policy & Financingof $9B total | $9B | $8.7B | +3% | ▼ 8 |
| 41 | New Mexico Health Care Authorityof $8.9B total | $8.9B | $9.4B | −5% | ▼ 12 |
| 42 | Leidos, Inc.of $8.5B total | $8.5B | $621.5M | — | ▲ 200 |
| 43 | Department of Health Human Servicesof $8.5B total | $8.5B | $8.1B | +5% | ▼ 8 |
| 44 | Triwest Healthcare Alliance Corpof $8B total | $8B | — | — | — |
| 45 | Arkansas Department of Human Servicesof $8B total | $8B | — | — | — |
| 46 | Illinois Department of Human Serviceof $7.8B total | $7.8B | $7.7B | +2% | ▼ 9 |
| 47 | Arkansas Department of Human Servicesof $7.8B total | $7.8B | $7.3B | +7% | ▼ 9 |
| 48 | Humana Government Business Incof $7.8B total | $7.8B | — | — | — |
| 49 | Oklahoma Health Care Authorityof $7.7B total | $7.7B | $6.6B | +17% | ▼ 8 |
| 50 | BAE Systems, Inc.of $7.4B total | $7.4B | $5M | — | ▲ 804 |
| 51 | Department of Education Californiaof $7.4B total | $7.4B | $13.3B | −45% | ▼ 30 |
| 52 | Booz Allen Hamilton Incof $7.3B total | $7.3B | $5.2M | — | ▲ 800 |
| 53 | Alabama Medicaid Agencyof $7B total | $7B | $6.2B | +14% | ▼ 8 |
| 54 | National Railroad Passenger Corporationof $6.9B total | $6.9B | $6.6B | +4% | ▼ 14 |
| 55 | L3Harris Technologies, Inc.of $6.3B total | $6.3B | $220.9M | — | ▲ 464 |
| 56 | IA Department of Human Servicesof $6.2B total | $6.2B | $6.3B | −2% | ▼ 14 |
| 57 | Ohio Department of Job & Family Servicesof $6.1B total | $6.1B | $6.9B | −11% | ▼ 18 |
| 58 | West Virginia Department of Health and Human Resourcesof $6.1B total | $6.1B | $6.2B | −1% | ▼ 14 |
| 59 | Department of Transportation Californiaof $5.7B total | $5.7B | $5.8B | −1% | ▼ 13 |
| 60 | Mississippi Division of Medicaidof $5.7B total | $5.7B | $5.6B | +1% | ▼ 12 |
| 61 | Texas Department of Transportationof $5.5B total | $5.5B | $5.8B | −4% | ▼ 14 |
| 62 | Miscellaneous Foreign Awardeesof $4.9B total | $4.9B | $4.1B | +20% | ▼ 6 |
| 63 | West Virginia Department of Health and Human Resourcesof $4.8B total | $4.8B | $4.6B | +5% | ▼ 11 |
| 64 | Department of Human Servicesof $4.8B total | $4.8B | $6.3B | −24% | ▼ 21 |
| 65 | Science Applications International Corporationof $4.7B total | $4.7B | $303.2M | — | ▲ 342 |
| 66 | New York State Education Departmentof $4.7B total | $4.7B | $4.9B | −5% | ▼ 16 |
| 67 | National Technology & Engineering Solutions of Sandia, LLCof $4.7B total | $4.7B | $1.2M | — | ▲ 804 |
| 68 | Triad National Security, LLCof $4.6B total | $4.6B | $6.1M | — | ▲ 782 |
| 69 | Atlantic Diving Supply, Inc.of $4.6B total | $4.6B | $1.1K | — | ▲ 876 |
| 70 | Science Applications International Corporationof $4.5B total | $4.5B | $4B | +14% | ▼ 11 |
| 71 | Nevada Department of Health & Human Servicesof $4.5B total | $4.5B | $4.5B | −1% | ▼ 18 |
| 72 | Puerto Rico Department of Healthof $4.4B total | $4.4B | $3B | +49% | ▲ 9 |
| 73 | Amerisourcebergen Drug Corpof $4.4B total | $4.4B | — | — | — |
| 74 | Battelle Memorial Instituteof $4.4B total | $4.4B | $104M | — | ▲ 721 |
| 75 | Nevada Department of Human Servicesof $4.3B total | $4.3B | $4.4B | −2% | ▼ 21 |
| 76 | New York State Division of Homeland Security & Emergency Servicesof $4.1B total | $4.1B | $9.1B | −55% | ▼ 45 |
| 77 | Government of District of Columbiaof $4.1B total | $4.1B | $3.8B | +8% | ▼ 15 |
| 78 | Maine Department of Health and Human Servicesof $4B total | $4B | $3.9B | +3% | ▼ 18 |
| 79 | Kansas Department of Health & Environmentof $4B total | $4B | $3.5B | +15% | ▼ 10 |
| 80 | TX Education Agencyof $3.9B total | $3.9B | $3.8B | +3% | ▼ 19 |
| 81 | General Electric Companyof $3.9B total | $3.9B | $8M | — | ▲ 764 |
| 82 | Nebraska Department of Health & Human Servicesof $3.8B total | $3.8B | $3.6B | +6% | ▼ 17 |
| 83 | United Nations World Food Programmeof $3.8B total | $3.8B | $4.7B | −18% | ▼ 32 |
| 84 | New York City Housing Authorityof $3.8B total | $3.8B | $3.5B | +8% | ▼ 16 |
| 85 | Utah Department of Health and Human Servicesof $3.7B total | $3.7B | $4.1B | −9% | ▼ 28 |
| 86 | CACI International Incof $3.7B total | $3.7B | $34.7M | — | ▲ 730 |
| 87 | Idaho Department of Health & Welfareof $3.7B total | $3.7B | $3.2B | +15% | ▼ 12 |
| 88 | Governor's Authorized Representativeof $3.7B total | $3.7B | $3.7B | −1% | ▼ 24 |
| 89 | Deloitte LLPof $3.6B total | $3.6B | — | — | — |
| 90 | Health Net Federal Services, LLCof $3.6B total | $3.6B | — | — | — |
| 91 | Department of Human Services Hawaiiof $3.6B total | $3.6B | $3.4B | +5% | ▼ 20 |
| 92 | Fluor Marine Propulsion, LLCof $3.5B total | $3.5B | — | — | — |
| 93 | Peraton Corp.of $3.5B total | $3.5B | $6.3M | — | ▲ 755 |
| 94 | Arizona Department of Economic Securityof $3.5B total | $3.5B | $3.1B | +13% | ▼ 17 |
| 95 | Texas Department of Agricultureof $3.5B total | $3.5B | $4.2B | −18% | ▼ 40 |
| 96 | Consolidated Nuclear Security, LLCof $3.3B total | $3.3B | — | — | — |
| 97 | Virginia Department of Social Servicesof $3.3B total | $3.3B | $3.5B | −6% | ▼ 30 |
| 98 | Florida Department of Educationof $3.3B total | $3.3B | $5.4B | −39% | ▼ 49 |
| 99 | KBR, Inc.of $3.3B total | $3.3B | $326.7M | +900% | ▲ 291 |
| 100 | Pfizer Incof $3.3B total | $3.3B | $1.4B | +141% | ▲ 30 |