| 1 | Health Care Services, California Department of0 awards | $112.5B | $100.9B | +12% | same |
| 2 | NYS Department of Health0 awards | $75B | $71.1B | +5% | same |
| 3 | Health & Human SVC Commn TX0 awards | $33B | $34B | −3% | same |
| 4 | PA Department of Human Services0 awards | $31.9B | $30B | +6% | same |
| 5 | Ohio Department of Medicaid0 awards | $27.7B | $24.6B | +13% | same |
| 6 | North Carolina Department of Health & Human Services0 awards | $27.7B | $23.7B | +17% | same |
| 7 | Florida Agency for Health Care Administration0 awards | $22.8B | $21.6B | +6% | same |
| 8 | Illinois Department of Healthcare & Family Services0 awards | $21.9B | $20.6B | +6% | ▲ 1 |
| 9 | Michigan Department of Health and Human Services0 awards | $20.9B | $21.1B | −1% | ▼ 1 |
| 10 | Human Services, New Jersey Department of0 awards | $18.1B | $15.7B | +15% | ▲ 2 |
| 11 | VA Department of Medical Assistance Service0 awards | $17.2B | $14.8B | +16% | ▲ 4 |
| 12 | Health Services Kentucky Cabinet for0 awards | $16.8B | $15.7B | +7% | ▼ 1 |
| 13 | The Commonwealth of Massachusetts0 awards | $16.8B | $15.4B | +9% | same |
| 14 | Indiana Family and Social Serv0 awards | $16.5B | $15.1B | +10% | same |
| 15 | Arizona Health Care Cost Containment System0 awards | $16.4B | $15.8B | +4% | ▼ 5 |
| 16 | Lousiana Department of Health0 awards | $14.6B | $13.5B | +8% | same |
| 17 | Oregon Health Authority-Public Health0 awards | $13.8B | $12.2B | +12% | ▲ 1 |
| 18 | Department of Social & Health Services0 awards | $13.7B | $12.1B | +13% | ▲ 1 |
| 19 | Georgia Department of Community Health0 awards | $13B | $11.9B | +9% | ▲ 1 |
| 20 | Minnesota Department of Human Services0 awards | $13B | $11.7B | +11% | ▲ 1 |
| 21 | Department of Social Services Misso0 awards | $12.9B | $13.1B | −2% | ▼ 4 |
| 22 | Finance & Administration Tennessee Depar0 awards | $11.9B | $10B | +19% | same |
| 23 | State of Colorado - Dept of Health Care Policy & Financing0 awards | $10B | $8.7B | +15% | same |
| 24 | State of Wisconsin Department of Health Services0 awards | $9.5B | $8.1B | +17% | same |
| 25 | New Mexico Health Care Authority0 awards | $8.6B | $7.5B | +14% | ▲ 1 |
| 26 | Department of Health Human Services0 awards | $7.9B | $7.6B | +4% | ▼ 1 |
| 27 | Oklahoma Health Care Authority0 awards | $7.9B | $7.5B | +6% | ▲ 1 |
| 28 | Department of Social Services Connecticut0 awards | $7.7B | — | — | — |
| 29 | IA Department of Human Services0 awards | $7.4B | $6.8B | +9% | same |
| 30 | Human Services, Arkansas Department of0 awards | $7.2B | $6.2B | +16% | ▲ 1 |
| 31 | Department of Social Services California0 awards | $6.7B | $7.5B | −10% | ▼ 4 |
| 32 | Alabama Medicaid Agency0 awards | $6.6B | $6.4B | +3% | ▼ 2 |
| 33 | Nevada Department of Human Services0 awards | $6.1B | $5.1B | +21% | ▲ 1 |
| 34 | Mississippi Division of Medicaid0 awards | $6B | $5.9B | +2% | ▼ 2 |
| 35 | Health and Human Resources, West Virginia Department of0 awards | $4.7B | $4.1B | +14% | ▲ 3 |
| 36 | Kansas Department of Health & Environment0 awards | $4.3B | $3.5B | +26% | ▲ 4 |
| 37 | Health and Human Services, Maine Department of0 awards | $3.9B | $3.6B | +9% | ▲ 2 |
| 38 | Nebraska Department of Health & Human Services0 awards | $3.8B | $3.1B | +21% | ▲ 5 |
| 39 | Utah Department of Health and Human Services0 awards | $3.7B | $4.7B | −20% | ▼ 4 |
| 40 | Idaho Department of Health & Welfare0 awards | $3.6B | $3.1B | +18% | ▲ 4 |
| 41 | District of Columbia, Government of0 awards | $3.6B | $3.4B | +6% | same |
| 42 | Puerto Rico Department of Health0 awards | $3.4B | $4.2B | −18% | ▼ 5 |
| 43 | New York State Office of Temporary & Disability Assistance0 awards | $3.3B | $3.4B | −1% | ▼ 1 |
| 44 | Merck Sharp & Dohme LLC0 awards | $2.9B | $2.9B | 0% | ▲ 1 |
| 45 | State of Rhode Island Department of Administration0 awards | $2.7B | $2.5B | +7% | ▲ 3 |
| 46 | State of Alaska Department of Health0 awards | $2.7B | $2.3B | +13% | ▲ 3 |
| 47 | Department of Human Services Hawaii0 awards | $2.3B | $2.6B | −11% | same |
| 48 | State of Montana Department of Health and Human Services0 awards | $2.3B | $2.1B | +8% | ▲ 4 |
| 49 | Health and Social Services, Delaware Dept of0 awards | $2.3B | $2.3B | 0% | ▲ 1 |
| 50 | New Hampshire Department of Health & Human Services0 awards | $2B | $1.7B | +16% | ▲ 4 |
| 51 | Human Services Vermont Agency of0 awards | $1.7B | $1.7B | +1% | ▲ 4 |
| 52 | Social Services South Dakota Department0 awards | $1.4B | $1.3B | +4% | ▲ 7 |
| 53 | North Dakota Department of Human Services0 awards | $1.2B | $1.1B | +18% | ▲ 11 |
| 54 | Florida Department of Children and Families0 awards | $1.2B | $2.1B | −42% | ▼ 3 |
| 55 | Children & Family Services, New York Office of0 awards | $1.2B | $1.4B | −14% | ▲ 2 |
| 56 | Texas Workforce Commission0 awards | $1.2B | $1.3B | −3% | ▲ 5 |
| 57 | Illinois Department of Human Service0 awards | $1.2B | $1.3B | −10% | ▲ 3 |
| 58 | Sanofi Vaccines US Inc.0 awards | $1.1B | $1.6B | −31% | ▼ 2 |
| 59 | Department of Insurance of the State of Georgia0 awards | $1B | $756.6M | +34% | ▲ 12 |
| 60 | Glaxosmithkline, LLC0 awards | $979.7M | $1.2B | −16% | ▲ 2 |
| 61 | Ohio Department of Job & Family Services0 awards | $967.4M | $1.8B | −45% | ▼ 8 |
| 62 | Maximus Federal Services, Inc.0 awards | $949.7M | $758.4M | +25% | ▲ 8 |
| 63 | The Johns Hopkins University0 awards | $900.9M | $927M | −3% | ▲ 3 |
| 64 | Regents of the University of California, San Francisco, the0 awards | $871.5M | $892.6M | −2% | ▲ 3 |
| 65 | General Dynamics Corporation0 awards | $839.3M | — | — | — |
| 66 | Ohio Department of Children and Youth0 awards | $827.4M | $139.3M | +494% | ▲ 183 |
| 67 | Leidos, Inc.0 awards | $793.6M | $1.1B | −29% | ▼ 4 |
| 68 | Regents of the University of Michigan0 awards | $767.6M | $785.8M | −2% | ▲ 1 |
| 69 | California Department of Child Support Services0 awards | $735.8M | $470.2M | +57% | ▲ 38 |
| 70 | Trustees of the University of Pennsylvania, the0 awards | $735.6M | $697.8M | +5% | ▲ 5 |
| 71 | Washington University, the0 awards | $732.7M | $750.9M | −2% | ▲ 1 |
| 72 | The Trustees of Columbia University in the City of New York0 awards | $722.5M | $872M | −17% | ▼ 4 |
| 73 | State of Wisconsin Dept of Children & Families0 awards | $722M | $737.4M | −2% | same |
| 74 | Pfizer Inc0 awards | $698.7M | $1.4B | −49% | ▼ 16 |
| 75 | The Leland Stanford Junior University0 awards | $692.8M | $639M | +8% | ▲ 8 |
| 76 | University of Pittsburgh - of the Commonwealth System of Higher Education0 awards | $691.7M | $674.3M | +3% | ▲ 2 |
| 77 | Yale Univ0 awards | $688.8M | $663.3M | +4% | ▲ 3 |
| 78 | Southwest Key Programs Inc0 awards | $666.9M | $972.5M | −31% | ▼ 13 |
| 79 | The General Hospital Corporation0 awards | $664.8M | $654M | +2% | ▲ 2 |
| 80 | Arizona Department of Economic Security0 awards | $644.3M | $708.1M | −9% | ▼ 6 |
| 81 | Duke University0 awards | $638.5M | $613.9M | +4% | ▲ 6 |
| 82 | Department of Human Services0 awards | $628.5M | $633.8M | −1% | ▲ 3 |
| 83 | Emory University0 awards | $616M | $555.1M | +11% | ▲ 13 |
| 84 | Florida Department of Education0 awards | $615.4M | $685.4M | −10% | ▼ 8 |
| 85 | Maryland Department of Human Services0 awards | $606.9M | $581.1M | +4% | ▲ 7 |
| 86 | University of California, San Diego0 awards | $594.2M | $572.3M | +4% | ▲ 8 |
| 87 | Human Services, Oklahoma Dept of0 awards | $580M | $667M | −13% | ▼ 8 |
| 88 | Icahn School of Medicine at Mount Sinai0 awards | $578.6M | $553.9M | +4% | ▲ 9 |
| 89 | Maryland Health Benefit Exchange0 awards | $577.8M | $526.7M | +10% | ▲ 12 |
| 90 | Tennessee Department of Human Services0 awards | $563.9M | $595.7M | −5% | ▼ 1 |
| 91 | University of Washington0 awards | $556.4M | $684.5M | −19% | ▼ 14 |
| 92 | Banking and Insurance, New Jersey Department of0 awards | $554.5M | $609.5M | −9% | ▼ 4 |
| 93 | University of North Carolina at Chapel Hill0 awards | $554.3M | $588.1M | −6% | ▼ 3 |
| 94 | University of California, Los Angeles0 awards | $545.8M | $558.3M | −2% | ▲ 1 |
| 95 | Public Health, California Department of0 awards | $533M | $578.2M | −8% | ▼ 2 |
| 96 | New York University0 awards | $528.7M | $584.3M | −10% | ▼ 5 |
| 97 | Department of Health Wyoming0 awards | $528.4M | $507.5M | +4% | ▲ 6 |
| 98 | Department of Transitional Assistan0 awards | $510.7M | $510.2M | 0% | ▲ 4 |
| 99 | Social Services, Virginia Department of0 awards | $510.5M | $550.5M | −7% | ▼ 1 |
| 100 | Department of Human Services Colorado0 awards | $508.3M | $628.8M | −19% | ▼ 14 |