| 01 | Drugs and BiologicalsPSC 6505 | $44.1B | $47.9B | −8% | same |
| 02 | Medical- Managed HealthcarePSC Q201 | $29.7B | $23.1B | +29% | ▲ 3 |
| 03 | Support- Professional: Engineering/TechnicalPSC R425 | $28.2B | $28.2B | 0% | ▼ 1 |
| 04 | Support- Professional: OtherPSC R499 | $24.8B | $23.6B | +5% | same |
| 05 | Aircraft, Fixed WingPSC 1510 | $22.7B | $24.4B | −7% | ▼ 2 |
| 06 | Combat Ships and Landing VesselsPSC 1905 | $17.2B | $16.6B | +4% | same |
| 07 | Operation of Miscellaneous BuildingsPSC M1JZ | $15.3B | $13.6B | +12% | same |
| 08 | IT and Telecom - Business Application/Application Development Support Services (Labor)PSC DA01 | $12.6B | $6.3B | +100% | ▲ 6 |
| 09 | Support- Professional: Program Management/SupportPSC R408 | $12.3B | $11.4B | +8% | ▼ 1 |
| 10 | Guided MissilesPSC 1410 | $11.4B | $8.8B | +29% | ▲ 1 |
| 11 | Liquid Propellants and Fuels, Petroleum BasePSC 9130 | $11.3B | $5.3B | +111% | ▲ 7 |
| 12 | Oper of Govt R&D GOCO FacilitiesPSC M181 | $10.8B | $9.3B | +17% | ▼ 2 |
| 13 | Gas Turbines and Jet Engines, Aircraft, Prime Moving; and ComponentsPSC 2840 | $9.1B | $5B | +81% | ▲ 6 |
| 14 | Social- Government Health Insurance ProgramsPSC G007 | $8.4B | $4.9B | +69% | ▲ 6 |
| 15 | Medical and Surgical Instruments, Equipment, and SuppliesPSC 6515 | $7.8B | $5.7B | +38% | ▲ 1 |
| 16 | IT and Telecom- Other IT and TelecommunicationsPSC D399 | $7.6B | $10.8B | −29% | ▼ 7 |
| 17 | Support- Management: Logistics SupportPSC R706 | $7.5B | $8.1B | −8% | ▼ 5 |
| 18 | Construction of Miscellaneous BuildingsPSC Y1JZ | $6.8B | $4.2B | +61% | ▲ 6 |
| 19 | Maint/Repair/Rebuild of Equipment- Aircraft and Airframe Structural ComponentsPSC J015 | $6.5B | $6.6B | −1% | ▼ 6 |
| 20 | National Defense R&D Services; Department of Defense - Military; Experimental DevelopmentPSC AC13 | $5.4B | $3B | +84% | ▲ 21 |
| 21 | Aircraft, Rotary WingPSC 1520 | $4.6B | $6.1B | −24% | ▼ 6 |
| 22 | Miscellaneous Aircraft Accessories and ComponentsPSC 1680 | $4.6B | $4.3B | +6% | same |
| 23 | National Defense R&D Services; Atomic Energy Defense Activities; R&D Administrative ExpensesPSC AC24 | $4.5B | $3.9B | +15% | ▲ 3 |
| 24 | Housekeeping- GuardPSC S206 | $4.4B | $4.3B | +3% | ▼ 1 |
| 25 | IT and Telecom - Business Application/Application Development Software as a ServicePSC DA10 | $4.2B | $2.2B | +89% | ▲ 28 |
| 26 | IT and Telecom - Business Application Software (Perpetual License Software)PSC 7A21 | $4.2B | $2.8B | +48% | ▲ 17 |
| 27 | Marine Lifesaving and Diving EquipmentPSC 4220 | $4.2B | $3.4B | +21% | ▲ 4 |
| 28 | Radar Equipment, Except AirbornePSC 5840 | $4.1B | $2.4B | +68% | ▲ 22 |
| 29 | Housekeeping- Facilities Operations SupportPSC S216 | $4B | $3.2B | +25% | ▲ 6 |
| 30 | Precious Metals Primary FormsPSC 9660 | $4B | $4B | 0% | ▼ 5 |
| 31 | Nuclear ReactorsPSC 4470 | $3.9B | $3.5B | +12% | ▼ 1 |
| 32 | IT and Telecom- Integrated Hardware/Software/Services Solutions, Predominantly ServicesPSC D318 | $3.7B | $4.6B | −19% | ▼ 11 |
| 33 | National Defense R&D Services; Defense-Related Activities; Applied ResearchPSC AC32 | $3.7B | $1.6B | +136% | ▲ 46 |
| 34 | Support- Administrative: OtherPSC R699 | $3.6B | $3.4B | +8% | ▼ 1 |
| 35 | Transportation/Travel/Relocation- Transportation: Space Transportation/LaunchPSC V126 | $3.6B | $3B | +22% | ▲ 5 |
| 36 | Operation of Government-Owned Contractor-Operated (GOCO) R&D FacilitiesPSC M1HA | $3.6B | $3B | +18% | ▲ 2 |
| 37 | Other Environmental ServicesPSC F999 | $3.5B | $3B | +14% | same |
| 38 | Support- Management: OtherPSC R799 | $3.4B | $3.9B | −12% | ▼ 11 |
| 39 | Laboratory Equipment and SuppliesPSC 6640 | $3.3B | $3.8B | −13% | ▼ 11 |
| 40 | Construction of Office BuildingsPSC Y1AA | $3.2B | $2.5B | +30% | ▲ 8 |
| 41 | R&D- Other Research and Development (Basic Research)PSC AZ11 | $3B | $3B | −1% | ▼ 5 |
| 42 | Support- Professional: Emergency Response/Disaster Planning/Preparedness SupportPSC R429 | $3B | $2.8B | +7% | ▲ 3 |
| 43 | Repair or Alteration of Miscellaneous BuildingsPSC Z2JZ | $2.8B | $1.8B | +54% | ▲ 23 |
| 44 | Combat, Assault, and Tactical Vehicles, TrackedPSC 2350 | $2.8B | $1B | +170% | ▲ 73 |
| 45 | Combat, Assault, and Tactical Vehicles, WheeledPSC 2355 | $2.8B | $3.4B | −19% | ▼ 13 |
| 46 | Airframe Structural ComponentsPSC 1560 | $2.7B | $2.5B | +8% | ▲ 3 |
| 47 | Meat, Poultry, and FishPSC 8905 | $2.6B | $2.3B | +17% | ▲ 5 |
| 48 | Medical- Evaluation/ScreeningPSC Q403 | $2.6B | $2.5B | +4% | ▼ 1 |
| 49 | Architect and Engineering- General: OtherPSC C219 | $2.6B | $1.7B | +50% | ▲ 23 |
| 50 | Electronic Countermeasures, Counter-Countermeasures and Quick Reaction Capability EquipmentPSC 5865 | $2.5B | $2.8B | −10% | ▼ 6 |
| 51 | Medical- OtherPSC Q999 | $2.5B | $5.5B | −55% | ▼ 34 |
| 52 | Maint/Repair/Rebuild of Equipment- Aircraft Components and AccessoriesPSC J016 | $2.4B | $2.4B | +3% | ▼ 1 |
| 53 | Fuel OilsPSC 9140 | $2.4B | $1.4B | +79% | ▲ 38 |
| 54 | Social- OtherPSC G099 | $2.3B | $2.6B | −10% | ▼ 8 |
| 55 | Support- Management: FinancialPSC R710 | $2.3B | $2.2B | +5% | ▼ 1 |
| 56 | Communications Security Equipment and ComponentsPSC 5810 | $2.3B | $2.1B | +7% | ▼ 1 |
| 57 | Space R&D Services; Space Flight, Research and Supporting Activities; Basic ResearchPSC AR11 | $2.3B | $1.7B | +35% | ▲ 17 |
| 58 | IT and Telecom - IT Management Support Services (Labor)PSC DF01 | $2.3B | $1.2B | +94% | ▲ 48 |
| 59 | National Defense R&D Services; Department of Defense - Military; Applied ResearchPSC AC12 | $2.2B | $1.4B | +58% | ▲ 28 |
| 60 | Guided Missile ComponentsPSC 1420 | $2.2B | $3.3B | −34% | ▼ 26 |
| 61 | Repair or Alteration of Office BuildingsPSC Z2AA | $2.1B | $2.1B | +3% | ▼ 4 |
| 62 | Fruits and VegetablesPSC 8915 | $2B | $3.7B | −44% | ▼ 33 |
| 63 | Reference Laboratory TestingPSC Q301 | $2B | $2.9B | −31% | ▼ 21 |
| 64 | Oper of Govt Other Industrial BldgPSC M159 | $2B | $1.8B | +13% | ▲ 6 |
| 65 | Information Technology SoftwarePSC 7030 | $2B | $3B | −34% | ▼ 26 |
| 66 | R&D- Space: Science/Applications (Applied Research/Exploratory Development)PSC AR22 | $2B | $2.1B | −6% | ▼ 7 |
| 67 | Maint/Repair/Rebuild of Equipment- Engines, Turbines, and ComponentsPSC J028 | $2B | $1.8B | +9% | ▲ 1 |
| 68 | Cargo and Tanker VesselsPSC 1915 | $1.9B | $203.3M | +843% | ▲ 307 |
| 69 | Environmental Systems Protection- Environmental RemediationPSC F108 | $1.9B | $1.7B | +12% | ▲ 4 |
| 70 | Housekeeping- Custodial JanitorialPSC S201 | $1.9B | $1.8B | +5% | ▼ 1 |
| 71 | IT and Telecom - End User: Help Desk;Tier 1-2,Workspace,Print,Output,Productivity Tools (HW/Perp SW)PSC 7E20 | $1.9B | $1.6B | +14% | ▲ 7 |
| 72 | Construction of DamsPSC Y1KA | $1.9B | $471.3M | +294% | ▲ 155 |
| 73 | Non-Nuclear Ship Repair (East)PSC J998 | $1.8B | $1.9B | −10% | ▼ 10 |
| 74 | National Defense R&D Services; Atomic Energy Defense Activities; Experimental DevelopmentPSC AC23 | $1.7B | $1.7B | +5% | ▲ 1 |
| 75 | Support- Management: AdvertisingPSC R701 | $1.7B | $1.4B | +27% | ▲ 17 |
| 76 | Non-Nuclear Ship Repair (West)PSC J999 | $1.7B | $1.9B | −10% | ▼ 11 |
| 77 | Unmanned AircraftPSC 1550 | $1.7B | $1.2B | +34% | ▲ 21 |
| 78 | Construction of Other Administrative Facilities and Service BuildingsPSC Y1AZ | $1.6B | $1.5B | +12% | ▲ 4 |
| 79 | Space VehiclesPSC 1555 | $1.6B | $1.3B | +26% | ▲ 15 |
| 80 | Transportation/Travel/Relocation- Transportation: Marine CharterPSC V124 | $1.6B | $1.3B | +25% | ▲ 17 |
| 81 | IT and Telecom - Service Delivery Support Services: ITSM, Operations Center, Project/PM (Labor)PSC DD01 | $1.6B | $916.5M | +70% | ▲ 49 |
| 82 | Radar Equipment, AirbornePSC 5841 | $1.5B | $1.6B | −6% | ▼ 5 |
| 83 | Passenger Motor VehiclesPSC 2310 | $1.5B | $1.5B | +6% | same |
| 84 | Construction of Other Non-Building FacilitiesPSC Y1PZ | $1.5B | $1.1B | +39% | ▲ 25 |
| 85 | R&D- Other Research and Development (Applied Research/Exploratory Development)PSC AZ12 | $1.5B | $2.1B | −29% | ▼ 29 |
| 86 | Utilities- ElectricPSC S112 | $1.5B | $1B | +44% | ▲ 30 |
| 87 | IT and Telecom- Facility Operation and MaintenancePSC D301 | $1.5B | $2.1B | −28% | ▼ 29 |
| 88 | National Defense R&D Services; Atomic Energy Defense Activities; Applied ResearchPSC AC22 | $1.5B | $1.1B | +30% | ▲ 20 |
| 89 | Transportation/Travel/Relocation- Transportation: Air CharterPSC V121 | $1.4B | $786.7M | +84% | ▲ 59 |
| 90 | National Defense R&D Svcs; Department of Defense - Military; R&D Facilities & Maj EquipPSC AC15 | $1.4B | $1.2B | +19% | ▲ 13 |
| 91 | Guided Missile Systems, CompletePSC 1425 | $1.4B | $2B | −27% | ▼ 29 |
| 92 | IT and Telecom - Compute: Servers (Hardware and Perpetual License Software)PSC 7B22 | $1.4B | $1.4B | +5% | ▼ 3 |
| 93 | Support- Administrative: Mailing/DistributionPSC R604 | $1.4B | $2B | −28% | ▼ 32 |
| 94 | Support- Management: Contract/Procurement/Acquisition SupportPSC R707 | $1.4B | $1.4B | 0% | ▼ 8 |
| 95 | Natural Resources/Conservation- Forest-Range Fire Suppression/PresuppressionPSC F003 | $1.4B | $966.3M | +46% | ▲ 31 |
| 96 | Construction of Highways, Roads, Streets, Bridges, and RailwaysPSC Y1LB | $1.4B | $1.2B | +19% | ▲ 9 |
| 97 | BombsPSC 1325 | $1.4B | $1.8B | −24% | ▼ 30 |
| 98 | Health R&D Services; Health Care Services; Applied ResearchPSC AN12 | $1.4B | $1.4B | −3% | ▼ 14 |
| 99 | IT and Telecom- Systems DevelopmentPSC D302 | $1.4B | $2B | −31% | ▼ 39 |
| 100 | R&D- Defense System: Electronics/Communication Equipment (Basic Research)PSC AC61 | $1.4B | $1.4B | −5% | ▼ 15 |